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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Geldanamycin
5 mg
photos non contractuelles
Détails Produit
Product description: Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Destabilizes several oncogene and proto-oncogene products. Potent nuclear hormone receptor family inhibitor.
Alternate Names/Synonyms: NSC122750; BRN1633093; U-29135
Product Type: Chemical
Molecular Formula: C29H40N2O9
Molecular Weight: 560.6
CAS: 30562-34-6
Source / Host: Isolated from Streptomyces hygroscopicus.
Purity: >98% (HPLC)
InChiKey: QTQAWLPCGQOSGP-GAEFGYQESA-N
Appearance Yellow solid.
Solubility: Soluble in methanol or DMSO; insoluble in water.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
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