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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Hederacoside C
50 mg
photos non contractuelles
Détails Produit
Product description: Chemical. CAS: 14216-03-6. Formula: C59H96O26. MW: 1221.38. Hederacoside C is a major bioactive constituent isolated from Hedera helix L. It exhibits biological properties such as antibacterial, expectorant, bronchodilator, bronchospasmolytic and anti-inflammatroy effects. It is widely used in the treatment of respiratory disorders involving acute respiratory infections, chronic inflammatory bronchitis and productive coughs. It reduces TNF-alpha, IL-1beta, IL-6, COX-2, and nitric oxide synthase (NOS) levels in a concentration-dependent manner and IL-1 receptor-associated kinase-1 (IRAK1) activity. It reduces scopolamine-induced memory impairment. Hederacoside C markedly suppressed TLR2 and TLR4 expressions by attenuating the MAPKs (p38, ERK, JNK) and NF-kappa (p65 and IkappaBalpha) pathways followed by decreasing the phosphorylation of p38, ERK, JNK, p65, and IkappaBalpha.
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