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Product Details | |
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Synonyms | IL-33 (human) (C208S/C232S Mutant):Fc Knobs-into-Holes (human) (rec.); Interleukin-33 (human) (C208S/C232S Mutant); IL-1F11; NF-HEV |
Product Type | Protein |
Properties | |
Source/Host | HEK 293 cells |
Sequence |
Human IL-33 (aa 112-270) (with mutations C208S and C232S to protect IL-33 from oxidation) is fused at the C-terminus to the Fc portion of human IgG1 (Knobs-into-Holes technology) (see reference: J.B. Ridgway, et al.; Protein Eng. 9, 617 (1996)). |
Crossreactivity | Human Mouse |
Specificity |
Binds to human and mouse ST2. |
MW | ~55kDa and 28 kDa (SDS-PAGE) |
Purity | ≥95% (SDS-PAGE) |
Endotoxin Content | <0.01EU/μg purified protein (LAL test). |
Concentration | After reconstitution: 1mg/ml |
Reconstitution | Reconstitute with 50μl sterile water. |
Formulation | Lyophilized. Contains PBS |
Protein Negative Control | |
Other Product Data |
UniProt link Q2YEJ5: Interleukin-33 (human) |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions. |
Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | ![]() |
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