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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product Description: Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function.
Alternate Names/Synonyms: Interleukin-33 Receptor; IL1RL1; DER4; ST2
Product type: Protein
Source / Host: CHO cells
Sequence: The extracellular domain of mouse IL-33R [ST2] (aa 27-342) is fused to the N-terminus of the Fc region of mouse IgG2a.
Species Crossreactivity: Mouse
SBiological Activity: Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely.
TAGs: Fc
Purity: >98% (SDS-PAGE)
Endotoxin: <0.06EU/µg protein (LAL test; Lonza).
Formulation: Lyophilized from 0.2µm-filtered solution in PBS.
Handling Advice: Avoid freeze/thaw cycles.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: BLUE ICE
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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