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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Momelotinib
50 mg
photos non contractuelles
Détails Produit
Product description: CYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F mutant . Using ATP kinase assays IC(50) values for JAK1 (11nm), JAK2, (18nM), JAK2, JAK2V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC(50) < 100nM) detected against CDK2/cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKCµ), ROCK2, and TBK1 kinase as well.
Alternate Names/Synonyms: CYT387; Momelotinib
Product Type: Chemical
Molecular Formula: C23H22N6O2
Molecular Weight: 414.5
CAS: 1056634-68-4
Purity: >95%
InChiKey: ZVHNDZWQTBEVRY-UHFFFAOYSA-N
Appearance Solid.
Solubility: Soluble in DMSO.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.
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