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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: Chemical. CAS: 1426209-02-0. Formula: C90H141N25O26S4. MW: 2117.5. Isolated from Actinoplanes sp. Actagardin-related class II lantibiotic. Antibacterial with improved activity than actagardine against Staphylococcus spp. and Streptococcus spp. Shows significant activity against Gram-positive anaerobic bacteria, such as Clost. difficile, Clostridium butyricum, Clostridium perfringens and Peptostreptococcus asaccharolyticus. Most probably inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II (Lipid II), a key intermediate in peptidoglycan biosynthesis. Potential novel antimicrobial agent for the treatment of infections caused by Gram-positive pathogens including resistant strains.
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