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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Narciclasine
500 µg
photos non contractuelles
Détails Produit
Product description: Chemical. CAS: 29477-83-6. Formula: C14H13NO7. MW: 307.3. Plant growth modulator/inhibitor.Anticancer agent. Exhibits antiproliferative and pro-apoptotic effects in carcinoma cells and displays cytotoxic activity against a panel of 60 cancer cell lines. Shown to promote autophagy-induced apoptosis and to slow cell cycle progression.Inhibits protein synthesis by interacting with the 60S ribosome subunit.Regulates the Rho/ROCK/LIM kinase/cofilin pathway. Stimulates RhoA activation and induces actin polymerization.Anti-obesity agent. Attenuates diet-induced obesity (DIO) in mice by promoting oxidative metabolism in skeletal muscle and energy expenditure.Anti-inflammatory agent suppressing NF-kappaB-dependent gene transcription.Antiviral agent in vitro.Antifungal agent.Shown to inhibit amyloid plaque formation in an Alzheimer's disease model.
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