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10 mg

Ref. SYN-1194-M010
SynKinase
1220699-06-8

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Neuf 724.00 H.T.

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Détails Produit

Product description: PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50) of 9.1nM for the PI3K family when tested AKT phosphorylation in BT20 cells. In direct kinase assays, PF-04979064 has potent Ki values against PI3Kalpha (Ki= 0.13nM human, 0.299nM mouse) and PI3Kgamma (Ki=0.111nM), and PI3Kdelta (Ki=0.122nM). In contrast, Ki values for non-PI3K kinases such as mTOR were 10X higher at 1.42 nM.

Alternate Names/Synonyms: PF04979064

Product Type: Chemical

Molecular Formula: C24H26N6O3

Molecular Weight: 446.5

CAS: 1220699-06-8

Purity: >95%

InChiKey: GACQNUHFDBEIQH-HNNXBMFYSA-N

Appearance Solid.

Solubility: Soluble in DMSO.

Short Term Storage: +4°C

Long Term Storage: +4°C

Shipping: AMBIENT

Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.

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