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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50) of 9.1nM for the PI3K family when tested AKT phosphorylation in BT20 cells. In direct kinase assays, PF-04979064 has potent Ki values against PI3Kalpha (Ki= 0.13nM human, 0.299nM mouse) and PI3Kgamma (Ki=0.111nM), and PI3Kdelta (Ki=0.122nM). In contrast, Ki values for non-PI3K kinases such as mTOR were 10X higher at 1.42 nM.
Alternate Names/Synonyms: PF04979064
Product Type: Chemical
Molecular Formula: C24H26N6O3
Molecular Weight: 446.5
CAS: 1220699-06-8
Purity: >95%
InChiKey: GACQNUHFDBEIQH-HNNXBMFYSA-N
Appearance Solid.
Solubility: Soluble in DMSO.
Short Term Storage: +4°C
Long Term Storage: +4°C
Shipping: AMBIENT
Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.
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