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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Phomopsin A
500 µg
photos non contractuelles
Détails Produit
Product description: Chemical. CAS: 64925-80-0. Formula: C36H45ClN6O12. MW: 789.2. Isolated from Phomopsis leptostromiformis. Macrocyclic heptapeptide mycotoxin. Potent anti-mitotic compound that can cause cell death. Microtubule assembly inhibitor. Binds selectively to dimeric tubulin, inhibiting the formation of the microtubule spindle to block cell division. Binds at a site different from the colchicine binding site and overlapping the vinblastine binding site. Inhibits tubulin-dependent GTP hydrolysis. Binds beta-tubulin from higher organisms but not alpha-tubulin or fungal mycelial tubulin. Causes lupinosis (a degenerative disorder) in livestock fed infected lupins.
Alternate Names/Synonyms: PHO-A; NSC 381839
Product Type: Chemical
Molecular Formula: C36H45ClN6O12
Molecular Weight: 789.2
CAS: 64925-80-0
Source / Host: Isolated from Phomopsis leptostromiformis.
Purity: >98% (HPLC, TLC)
InChiKey: FAFRRYBYQKPKSY-KBIMZEDXSA-N
Appearance: White solid.
Solubility: Soluble in DMSO (10mg/ml), ethanol, methanol (5mg/ml) or DMF.
Short Term Storage: +4°C
Long Term Storage: -20°C
Long Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.
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