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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: R428 is a selective inhibitor of the receptor tyrosine kinase AXL. R428 blocks the catalytic and procancerous activities of AXL in vitro. 428 inhibits AXL at low nanomolar values and blocked AXL-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Reported IC(50) values are 11-14nM .
Alternate Names/Synonyms: R-428
Product Type: Chemical
Molecular Formula: C30H34N8
Molecular Weight: 506.6
CAS: 1037624-75-1
Purity: >95%
InChiKey: KXMZDGSRSGHMMK-VWLOTQADSA-N
Appearance Solid.
Solubility: Soluble in DMSO or ethanol.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.
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