RELM-beta (human) Matched Pair Detection Set

Product description: Matched Pair Detection Set. Detects human RELM-beta. Does not cross-react with human adiponectin, mouse adiponectin, human RBP4, human Nampt, human vaspin, human GPX3, human ANGPTL3, human progranulin, human leptin, human resistin, human IL-33, human sirtuin 1, human clusterin, mouse resistin, human FABP4. Colorimetric assay. Sample Types: . Range: 0.016 to 1ng/ml. Sensitivity: 10pg/ml. RELM-beta is a 19kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. RELM-beta has been suggested to play a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly, the molecular structure of RELM-beta is highly homologous to that of the adipose-derived cytokine resistin. The specific and sensitive RELM-beta Matched Pair Detection Set might detect RELM-beta in serum of gut-inflamed patients (e.g. inflammatory bowel diseases, Crohn disease and ulcerative colitis). Natural levels of RELM-beta were seen in stool, but were not detectable in the serum or other cell culture models of healthy human patients. Further testing are ongoing.

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