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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: Chemical. CAS: 501-36-0. Formula: C14H12O3. MW: 228.2. Resveratrol Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Potent phenolic antioxidant found in grapes and red wine. Eicosanoid synthesis and platelet aggregation inhibitor. Chemopreventive. Specific inhibitor of cyclooxygenase-1 (COX-1). Anti-inflammatory, anticancer and antiproliferative compound. Apoptosis and autophagy inducer. Potent SIRT1 (sirtuin 1) activator. Senescence modulator. Cardioprotective and neuroprotective. Adipogenesis inhibitor. Resveratrol Lipodisq is based on a nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilized by a chaperone molecule annulus. Internal properties of the phospholipid membrane support the disposition and stabilization of drug molecule candidates and preserve the native conformation of membrane molecules. The resulting encapsulated actives are rendered water-soluble and specialized for intra-cellular penetration/delivery via endosomal uptake mechanisms. Lipodisq solutions show a good safety profile and are suitable for in vitro and in vivo investigations.
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