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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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SGX-523
10 mg
photos non contractuelles
Détails Produit
Product description: SGX523 is an ATP-competitive, triazolopyridazine-based inhibitor of MET at an IC(50) of 4nM. SGX523 has higher affinity for the unphosphorylated form of MET (Ki = 2.7nM) than the more active phospho-enzyme (Ki = 23nM). In a broad panel of 213 kinases, SGX523 was extremely selective, with no inhibition >36%, suggesting IC(50) values > 1µM, including the closely-associated RON kinase.
Alternate Names/Synonyms: SGX523
Product Type: Chemical
Molecular Formula: C18H13N7S
Molecular Weight: 359.4
CAS: 1072116-01-8
Purity: >95%
InChiKey: BCZUAADEACICHN-UHFFFAOYSA-N
Appearance Solid.
Solubility: Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.
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