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100 mg

Ref. SYN-1155-M100
SynKinase
1072116-01-8

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Détails Produit

Product description: SGX523 is an ATP-competitive, triazolopyridazine-based inhibitor of MET at an IC(50) of 4nM. SGX523 has higher affinity for the unphosphorylated form of MET (Ki = 2.7nM) than the more active phospho-enzyme (Ki = 23nM). In a broad panel of 213 kinases, SGX523 was extremely selective, with no inhibition >36%, suggesting IC(50) values > 1µM, including the closely-associated RON kinase.

Alternate Names/Synonyms: SGX523

Product Type: Chemical

Molecular Formula: C18H13N7S

Molecular Weight: 359.4

CAS: 1072116-01-8

Purity: >95%

InChiKey: BCZUAADEACICHN-UHFFFAOYSA-N

Appearance Solid.

Solubility: Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: AMBIENT

Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.

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