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50 µg

Ref. SBB-TR0016-C050
SOUTH BAY BIO

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Neuf 183.00 H.T.

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Détails Produit

Product Description: Ubiquitin is a highly conserved protein that plays a major role in the ubiquitination pathway, which is conserved from yeast to mammals. Ubiquitination, the conjugation of ubiquitin to other proteins through a covalent bond between its C-terminal glycine and the epsilon-amino group of lysine residues or the alpha-amino group of an N- terminal methionine onto proteins is essential for many cellular processes primarily linked to protein degradation. This process involves three steps with specific groups of enzymes in an ATP depended manner, which are activation with ubiquitin-activating enzymes (E1s), conjugation with ubiquitin-conjugating enzymes (E2s) and ligation with ubiquitin ligases (E3s).

Alternate Names/Synonyms: UBB; Ubiquitin B

Product type: Protein

Source / Host: E. coli

Sequence: Human ubiquitin (aa1-76) is site-specifically conjugated to a single fluorescein (6-FAM) moiety. All lysines are available along with a fully functional C-terminus, making it ideal for chain formation using the E1-E2 and E3 conjugation cascade.

Species Crossreactivity: Human

Molecular Weight: ~9kDa

Labels - Conjugates: 6-FAM

Purity: >98% (LCMS)

Concentration: Lot dependent.

Formulation: Liquid. In 50mM HEPES pH 7.5, 50mM sodium chloride.

Handling Advice: Aliquot to avoid freeze/thaw cycles. Protect from light.

Short Term Storage: -20°C

Long Term Storage: -80°C

Shipping: DRY ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -80°C.

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