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50 µg

Ref. SBB-PS0001-C050
SOUTH BAY BIO

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Neuf 198.00 H.T.
en stock

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Détails Produit

Product Description: Ubiquitin is a 76 amino acid post-translational modifier expressed throughout all tissues in eukaryotic organisms. The many roles of ubiquitin modification include proteasomal degradation, signal transduction, inflammatory response and DNA damage repair. Ubiquitin modification occurs through a pyramidal cascade of an E1 activating enzyme, E2 conjugating enzymes and an E3 ubiquitin ligase. This enzymatic cascade results in modification of a epsilon-amine of a lysine residue on a substrate protein. Substrates may either be mono- or poly-ubiquitinated by M1, K6, 11, 27, 29, 33, 48 or 63 linkages. Removal of ubiquitin from a substrate protein occurs via deconjugating enzymes, of which there are nearly 100 known enzymes with various specificities.

Alternate Names/Synonyms: UBB; Ubiquitin B

Product type: Protein

Source / Host: E. coli

Sequence: Human ubiquitin (aa1-76) conjugated at the C-terminus to a quenched Rhodamine 110 dye.

Species Crossreactivity: Human

Molecular Weight: ~9kDa

Labels - Conjugates: Rhodamine

Purity: >99% (LCMS)

Concentration: Lot dependent.

Formulation: Liquid. In 50mM MES pH 6.0.

Handling Advice: Aliquot to avoid freeze/thaw cycles. Protect from light.

Short Term Storage: -80°C

Long Term Storage: -80°C

Shipping: DRY ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -80°C.

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