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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: Fumitremorgin-type alkaloid. Tremorgenic neurotoxic mycotoxin. Selective blocker of KCa1.1 (high-conductance Ca2+-activated K+; BK; maxi-K) channels. Decreases GABA levels in CNS. Increases spontaneous glutamate and aspartate release. At toxic doses, increases the number and decreases the affinity of DHP receptors in rat cortex. Cell cycle inhibitor at the M phase. Inhibits calmodulin and PKC activity. Has apoptotic effects on human T lymphocytes. Stimulates the growth of seedling roots of buckwheat.
Alternate Names/Synonyms: NA 209A; TR 1
Product Type: Chemical
Molecular Formula: C27H33N3O7
Molecular Weight: 511.6
CAS: 12771-72-1
Source / Host: Isolated from Aspergillus fumigatus.
Purity: >98% (HPLC)
InChiKey: LRXYHMMJJCTUMY-GWXUGYLUSA-N
Appearance White to off-white solid.
Solubility: Soluble in DMSO, 100% ethanol, methanol or dichloromethane.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
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