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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: YM-201636 is a cell-permeable and selective inhibitor of PIKfyve (IC(50) of 33nM). It disrupts retroviral budding from cells, apparently by interfering with the endosomal sorting complex required for transport (ESCRT) machinery. In adipocytes, YM-201636 also inhibits basal and insulin-activated 2-deoxyglucose uptake (IC(50) of 54nM).
Alternate Names/Synonyms: YM-201636
Product Type: Chemical
Molecular Formula: C25H21N7O3 . HCl
Molecular Weight: 467.4 . 36.5
CAS: 371942-69-7 (free base)
Purity: >95%
InChiKey: FZSHKSKFIDALKO-UHFFFAOYSA-N
Appearance Solid.
Solubility: Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C.
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