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100 µg

Ref. ANC-268-030
Ancell Corporation

photos non contractuelles

Neuf 388.00 H.T.

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Détails Produit

Product description: Monoclonal Antibody. Isotype: Mouse IgMkappa. Clone: ANC7D6. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.

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