anti-CD357 [GITR] (human), mAb (ANC7D6) (Biotin)

Product description: Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.

Alternate Names/Synonyms: GITR; Glucocorticoid-induced TNF Receptor; AITR; Activation-inducible TNF-related; TNFRSF18

Product Type: Monoclonal Antibody

Clone: ANC7D6

Isotype: Mouse IgMkappa

Immunogen: Recombinant human GITR, PHA stimulated human PBL.

Labels - Conjugates: Biotin

Applications: ELISA, FACS

Species Crossreactivity: Human

Short Term Storage: +4°C

Long Term Storage: +4°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.

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