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10 ug

Ref. AG-40B-0234-C010
AdipoGen Life Sciences

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Neuf 400.00 360.00 H.T.

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Détails Produit

Product Details
Synonyms IL-2 Switch-2 (monomeric):Fc Knobs-into-Holes (human) (rec.); Interleukin-2; T Cell Growth Factor; TCGF; IL-2 pH resistant; pH-selective IL-2 Mutein
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence

The extracellular domain of human IL-2 (aa 21-153) (mutant pH-resistant Switch-2 containing mutations T37H, R38L, T41S, F42Y, and K43G) is fused at the C-terminus to the Fc portion of human IgG1 (Knobs-into-Holes technology) (see reference: J.B. Ridgway, et al.; Protein Eng. 9, 617 (1996)).

Crossreactivity Human
Mouse
MW ~45kDa and 28kDa (SDS-PAGE)
Purity ≥95% (SDS-PAGE)
Endotoxin Content <0.01EU/μg protein (LAL test).
Concentration After reconstitution:
for 10µg size: 0.1mg/ml
for 100µg size: 1mg/ml
Reconstitution Reconstitute with 100μl endotoxin-free water.
Formulation Lyophilized. Contains PBS.
Protein Negative Control

Fc-KIH (human) IgG1 Control (rec.) (Prod. No. AG-35B-0015)

Other Product Data

Uniprot link P60568 : IL-2 (human)
 

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF