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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: ANO1 is a calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. ANO1 acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. Its overexpression was reported in esophageal squamous cell carcinoma and breast cancer progression.
Alternate Names/Synonyms: Anoctamin-1; DOG1
Product Type: Recombinant Antibody
Clone: RM440
Isotype: Rabbit IgG
Immunogen: A peptide corresponding to the internal region of human ANO1.
Applications: IHC
Species Crossreactivity: Human
Specificity: This antibody reacts to human ANO1.
Concentration: N/A
Long Term Storage: -20°C
Shipping: BLUE ICE
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.
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