anti-beta-Tubulin, mAb (AXO45)

Product description: The beta-tubulin monoclonal antibody (AXO45) was developed by isolating the cilia from unicellular multiciliated Paramecium and purifying the core microtubule-based structures of the cilia, the axonemes. These axonemes were electrophoresed on a SDS-PAGE and the tubulin band was used as an antigen to develop monoclonal antibodies targeting both alpha- and beta-tubulin (A.M. Callen, et al.; 1994). The antibody AXO45 recognizes the C-terminal region between residues 257 and 442 of beta-tubulin. Although the antibody was raised against the beta-tubulin found in cilia, it is able to recognize beta-tubulin of all microtubule networks, indicating that it can potentially recognize different isotypes of beta-tubulin found in mammals.

Alternate Names/Synonyms: Tubulin beta Chain; Tubulin beta-5 Chain

Product Type: Monoclonal Antibody

Clone: AXO45

Isotype: Mouse IgG1

Immunogen: Axonemal tubulin from the ciliate Paramecium electroeluted from the 55 kDa band of the SDS-PAGE gel.

Applications: ICC, IHC, IP, WB

Species Crossreactivity: Ciliates, Human, Mouse

Specificity: Detects almost all isotypes of beta-tubulin specifically in cells and tissues of mouse, human and ciliates.

Concentration: 1mg/ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 month after receipt when stored at +4°C. Stable for at least 1 year after receipt when stored at -20°C.

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