anti-Bmf, mAb (9G10)

Product description: Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

Alternate Names/Synonyms: Bcl-2-modifying Factor

Product Type: Monoclonal Antibody

Clone: 9G10

Isotype: Rat IgG2akappa

Immunogen: Recombinant mouse Bmf.

Applications: FACS, IP, WB

Species Crossreactivity: Human, Mouse

Specificity: Recognizes human and mouse Bmf. Detects several cross-reactivity bands of unknown identity in mice by western blot.

Endotoxin: <0.1EU/µg purified protein (LAL test; Lonza).

Concentration: 1mg/ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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