anti-BOB-1 (human), Rabbit Monoclonal (RM378)

Product description: BOB-1 (OBF-1; POU domain class 2-associating factor 1) is a transcriptional co-activator that interacts with the transcription factors OCT-1 or OCT-2 in regulating transcription of immunoglobulin genes. BOB-1 is expressed principally by B-cell lymphocytes. In normal tonsil, the germinal center B cells all express BOB-1, while only scattered cells in the mantle zone express this protein. Expression of BOB-1, OCT-2 and PU.1 transcription factors are often down-regulated in classic Hodgkin lymphomas, in contrast to many cases of diffuse large B-cell lymphoma.

Alternate Names/Synonyms: POU Domain Class 2-associating Factor 1; OBF-1; OCA-B; OCT-binding Factor 1

Product Type: Recombinant Antibody

Clone: RM378

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to the C-terminus of human BOB-1/OBF-1.

Applications: IHC, WB

Species Crossreactivity: Human

Specificity: This antibody reacts to human BOB-1/OBF-1 (B-cell-specific coactivator) (POU domain class 2-associating factor 1).

Concentration: N/A

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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