anti-CD13 (human), Rabbit Monoclonal (RM403)

Product description: CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus an important cause of upper respiratory tract infections.

Alternate Names/Synonyms: Aminopeptidase N; AP-N; Alanyl Aminopeptidase; Myeloid Plasma Membrane Glycoprotein CD13; Aminopeptidase M; AP-M

Product Type: Recombinant Antibody

Clone: RM403

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to residues near the C-terminus of human CD13.

Applications: IHC, WB

Species Crossreactivity: Human

Specificity: This antibody reacts to human to CD13.

Concentration: N/A

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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