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Product description: CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
Alternate Names/Synonyms: 4-1BB; TNFRSF9
Product Type: Monoclonal Antibody
Clone: M4173
Isotype: Rat IgG1kappa
Immunogen: Recombinant mouse CD137.
Applications: FACS, WB
Species Crossreactivity: Mouse
Specificity: Recognizes mouse CD137. Detects a band of ~40kDa by Western blot. Does not cross-react with human CD137.
Concentration: 1mg/ml
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: BLUE ICE
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.
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