anti-CD40L [CD154] (human), mAb (24-31) (R-PE)

Product description: Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. CD154 has been shown to be hyperexpressed by B and T cells in SLE patients. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells and macrophages indicating a possible role for the CD40-CD154 immunoregulatory signaling mechanism during inflammation and immunity in atherogenesis.

Product Type: Monoclonal Antibody

Clone: 24-31

Isotype: Mouse IgG1

Immunogen: Human sgp39 fusion protein.

Labels - Conjugates: R-PE

Applications: ELISA, FACS, FUNC (Blocking), IHC, WB

Species Crossreactivity: Human, Primate

Short Term Storage: +4°C

Long Term Storage: +4°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.

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