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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.
Alternate Names/Synonyms: B7-H2; ICOS Ligand; B7-like Protein Gl50; B7RP-1
Product Type: Monoclonal Antibody
Clone: ANC4E3
Isotype: Mouse IgG1kappa
Immunogen: Human Raji cells, recombinant human CD275-muIg.
Labels - Conjugates: Biotin
Applications: ELISA
Species Crossreactivity: Human
Short Term Storage: +4°C
Long Term Storage: +4°C
Shipping: BLUE ICE
Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.
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