anti-CD38 (human), Rabbit Monoclonal (RM388)

Product description: CD38, also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.

Alternate Names/Synonyms: ADP-ribosyl Cyclase/Cyclic ADP-ribose Hydrolase 1; ADPRC 1; T10

Product Type: Recombinant Antibody

Clone: RM388

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to residues near the C-terminus of human CD38 .

Applications: IHC, WB

Species Crossreactivity: Human

Specificity: This antibody reacts to human CD38.

Concentration: N/A

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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