anti-CD5 (human), Rabbit Monoclonal (RM314)

Product description: CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein, also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), peripheral blood dendritic cells and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 modulates T and B cell receptor signaling, thymocyte maturation and T-B cell interactions upon binding to ligands such as CD72. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.

Alternate Names/Synonyms: T-cell Surface Glycoprotein CD5

Product Type: Recombinant Antibody

Clone: RM314

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to the C-terminus of human CD5.

Applications: IHC, WB

Species Crossreactivity: Human

Specificity: This antibody reacts to human CD5.

Concentration: N/A

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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