anti-cGMP, Rabbit Monoclonal (RM467)

Product description: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).

Alternate Names/Synonyms: Cyclic Guanosine Monophosphate

Product Type: Recombinant Antibody

Clone: RM467

Isotype: Rabbit IgG

Immunogen: KLH-conjugated cGMP.

Applications: ELISA

Species Crossreactivity: All

Specificity: RM467 reacts to cGMP (Cyclic Guanosine Monophosphate). No cross-reactivity with other cyclic nucleotide or nucleoside phosphate.

Concentration: 1 mg/ml

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

Lien vers la Fiche Technique