anti-DLK1 (mouse), mAb (PF105B)

Product description: The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

Alternate Names/Synonyms: Protein Delta Homolog 1; Fetal Antigen 1; Preadipocyte Factor 1; Pref-1; FA1

Product Type: Monoclonal Antibody

Clone: PF105B

Isotype: Rat IgG2akappa

Immunogen: Recombinant mouse DLK1 (extracellular domain).

Applications: ELISA, WB

Species Crossreactivity: Mouse

Specificity: Recognizes mouse DLK1. Does not cross-react with human DLK1.

Concentration: ~1mg/ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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