anti-FOXP3 (human), mAb (ANCFX2D7) (FITC)

Product description: FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.

Alternate Names/Synonyms: Forkhead Box Protein P3; Scurfin; IPEX, JM2

Product Type: Monoclonal Antibody

Clone: ANCFX2D7

Isotype: Mouse IgG1kappa

Immunogen: Recombinant human FOXP3.

Labels - Conjugates: FITC

Applications: ELISA, FACS

Species Crossreactivity: Human

Specificity: Recognizes human FOXP3.

Concentration: 0.5mg/ml

Short Term Storage: +4°C

Long Term Storage: +4°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.

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