anti-FOXP3 (mouse), mAb (MF333F)

Product description: FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.

Alternate Names/Synonyms: Forkhead Box Protein P3; Scurfin

Product Type: Monoclonal Antibody

Clone: MF333F

Isotype: Rat IgG2akappa

Immunogen: Recombinant mouse FOXP3.

Applications: ELISA, ICC, IHC, WB

Species Crossreactivity: Mouse

Specificity: Recognizes mouse FOXP3. Detects a band of ~46-49kDa by Western blot.

Concentration: 1mg/ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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