anti-GAPDH, Rabbit Monoclonal (RM114)

Product description: GAPDH (Glyceraldehyde 3-phosphate dehydrogenase) is an enzyme of ~37kDa which is a tetramer composed of four identical 37-kDa subunits, containing a single catalytic thiol group each and critical to the enzyme's catalytic function. GADPH catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. In addition to this long established metabolic function, GAPDH has recently been implicated in several non-metabolic processes, including transcription activation, initiation of apoptosis, ER to Golgi vesicle shuttling, DNA repair. membrane fusion, microtubule bundling and age-related actions in neurodegenerative diseases.

Alternate Names/Synonyms: Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase GAPDH

Product Type: Recombinant Antibody

Clone: RM114

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to the C-terminus of GAPDH.

Applications: ICC, IHC, IP, WB, CHIP

Species Crossreactivity: Goat, Human, Monkey, Mouse

Specificity: This antibody reacts to GAPDH. RM114 shows strong reactivity to Human/Monkey GAPDH. RM114 shows weaker reactivity to Mouse, Goat GAPDH and may require higher antibody dilution usage.

Concentration: N/A

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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