anti-IL-23p19 (human), mAb (I 178G)

Product description: IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Alternate Names/Synonyms: Interleukin-23 Subunit p19; Interleukin-23 Subunit alpha; IL-23-A

Product Type: Monoclonal Antibody

Clone: I 178G

Isotype: Rat IgG2akappa

Immunogen: Recombinant human IL-23p19.

Applications: ELISA, WB

Species Crossreactivity: Human

Specificity: Recognizes human IL-23p19.

Concentration: 1mg/ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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