anti-INI1 (SNF5/SMARCB1), Rabbit Monoclonal (RM468)

Product description: INI1 (also known as SNF5 or SMARCB1) is a protein that is involved in the regulation of transcription, replication, and repair of DNA. It is a subunit of the SWI/SNF chromatin remodeling complex, which helps to open up DNA so that genes can be transcribed. INI1 is also involved in the repair of DNA damage, and it can help to prevent cancer cells from developing. Mutations or deletions of the INI1 gene are associated with a number of different cancers, including malignant rhabdoid tumor (MRT), atypical teratoid/rhabdoid tumor (AT/RT), and clear cell sarcoma of the kidney (CCSK).

Alternate Names/Synonyms: SNF5/SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; BRG1-associated factor 47 (BAF47)

Product Type: Recombinant Antibody

Clone: RM468

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to the C-terminus of human INI1 (SNF5/SMARCB1).

Applications: IHC, WB

Species Crossreactivity: Human

Specificity: RM468 reacts to human INI1 (SNF5/SMARCB1). This antibody may also react to mouse or rat INI1, as predicted by immunogen homology.

Concentration: 1 mg/ml

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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