anti-JAM1 (human), Rabbit Monoclonal (RM275)

Product description: JAM-1 (CD321; F11R; JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. JAM-1 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. JAM-1 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. JAM-1 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. JAM-1 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion and metastasis.

Alternate Names/Synonyms: Junctional Adhesion Molecule 1

Product Type: Recombinant Antibody

Clone: RM275

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to the N-terminus of human human JAM1 (Junctional adhesion molecule 1).

Applications: IHC, WB

Species Crossreactivity: Human

Specificity: This antibody reacts to human JAM1 (Junctional adhesion molecule 1).

Concentration: N/A

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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