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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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anti-LTbetaR (human), mAb (ANCLTR2/9E2) (Biotin)
100 µg
photos non contractuelles
Détails Produit
Product description: The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
Alternate Names/Synonyms: Lymphotoxin-beta Receptor; Tumor Necrosis Factor Receptor 2 Related Protein; Tumor Necrosis Factor C Receptor; Tumor Necrosis Factor Receptor Superfamily Member 3; TNFRSF3
Product Type: Monoclonal Antibody
Clone: ANCLTR2/9E2
Isotype: Mouse IgG1kappa
Immunogen: Recombinant Human LT.
Labels - Conjugates: Biotin
Applications: ELISA, FACS
Species Crossreactivity: Human
Short Term Storage: +4°C
Long Term Storage: +4°C
Shipping: BLUE ICE
Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.
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