anti-Netrin-4, mAb (Nely-1)

Product description: Netrin-4 is a 628 amino acid laminin-related secreted protein that promotes neurite elongation at low concentrations but inhibits neurite extension at high concentrations. Recent evidence suggest that Netrin family members act as regulators of both neuronal and vascular growth and are implicated in controling epithelial cell branching morphogenesis in the pancreas, breast and lung. Netrin-4 inhibits proliferation of a variety of human tumor cells. Netrin-4 also induces proliferation, migration, adhesion, tube formation and survival of human lymphatic endothelial cells and seems to function as a lymphangiogenic factor contributing to tumor dissemination.

Alternate Names/Synonyms: beta-Netrin; Hepar-derived Netrin-like Protein

Product Type: Monoclonal Antibody

Clone: Nely-1

Isotype: Mouse IgG1kappa

Immunogen: Netrin-4 (human) (Full-length)

Applications: ELISA, WB

Species Crossreactivity: Human, Mouse

Specificity: Recognizes human and mouse Netrin-4

Endotoxin: <0.1EU/µg purified protein (LAL test; Lonza).

Concentration: 1mg /ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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