anti-Nkx3.1 (human), Rabbit Monoclonal (RM430)

Product description: The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Alternate Names/Synonyms: Homeobox Protein Nkx-3.1; Homeobox Protein NK-3 Homolog A

Product Type: Recombinant Antibody

Clone: RM430

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to the N-terminus of human Nkx3.1.

Applications: IHC

Species Crossreactivity: Human

Specificity: RM430 reacts to human Nkx3.1.

Concentration: N/A

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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