anti-PIDD (mouse), mAb (Lise-1)

Product description: PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.

Alternate Names/Synonyms: p53-induced Protein with a Death Domain; Leucine-rich Repeat and Death Domain-containing Protein; Lrdd

Product Type: Monoclonal Antibody

Clone: Lise-1

Isotype: Mouse IgG2bkappa

Immunogen: Mouse PIDD (Death Domain).

Applications: WB

Species Crossreactivity: Mouse

Specificity: Recognizes mouse PIDD.

Endotoxin: <0.1EU/µg purified protein (LAL test; Lonza).

Concentration: 1mg/ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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