anti-Resistin (human), mAb (HRES106)

Product description: The adipokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) that are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM. Resistin is secreted by obese subcutaneous adipose tissue and impaired myotube thickness and nuclear fusion by activation of the classical NF-kappaB pathway. In human, resistin levels are increased in the serum of obese individuals and resistin is used as a severity marker of asthma.

Alternate Names/Synonyms: FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor

Product Type: Monoclonal Antibody

Clone: HRES106

Isotype: Mouse IgG2akappa

Immunogen: Recombinant human resistin.

Applications: ELISA

Species Crossreactivity: Human

Specificity: Recognizes human resistin. Does not cross-react with mouse resistin.

Concentration: 1mg/ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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