anti-S100-beta (human), Rabbit Monoclonal (RM304)

Product description: S100-beta (S100B) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma and type I diabetes.

Alternate Names/Synonyms: Protein S100-B

Product Type: Recombinant Antibody

Clone: RM304

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to the C-terminus of human S100-B.

Applications: IHC, WB

Species Crossreactivity: Human

Specificity: This antibody reacts to human S100-B (S-100 protein beta chain). It may also react to mouse or rat S100-B, as predicted by immunogen homology.

Concentration: N/A

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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