anti-Stearoyl-CoA Desaturase-1 (mouse), pAb

Product description: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.

Alternate Names/Synonyms: SCD1; Acyl-CoA Desaturase 1; Fatty Acid Desaturase 1

Product Type: Polyclonal Antibody

Immunogen: Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1.

Applications: ELISA, WB

Species Crossreactivity: Mouse

Specificity: Recognizes mouse SCD1. Detects a band of ~41kDa by Western Blot.

Concentration: 1mg/ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.

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