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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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anti-TRAIL-R1 (human), mAb (HS101) (FITC)
100 tests
photos non contractuelles
Détails Produit
Product description: TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Alternate Names/Synonyms: TRAIL Receptor 1; DR4; APO2; TNFRSF10A; CD261
Product Type: Monoclonal Antibody
Clone: HS101
Isotype: Mouse IgG1
Immunogen: Recombinant human TRAIL-R1 (DR4).
Labels - Conjugates: FITC
Applications: FACS, ICC
Species Crossreactivity: Human
Specificity: Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4.
Concentration: 1mg/ml
Short Term Storage: +4°C
Long Term Storage: +4°C
Shipping: BLUE ICE
Use & Stability: Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.
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