anti-TRB-3 (human), pAb

Product description: Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.

Alternate Names/Synonyms: Tribbles Homolog 3; Neuronal Cell death-inducible Putative Kinase; SINK; p65-interacting Inhibitor of NF-kappaB

Product Type: Polyclonal Antibody

Immunogen: Synthetic peptide corresponding to aa 112-125 (A112RLPPHKHVARPTE125) of human TRB-3.

Applications: ELISA, IHC, WB

Species Crossreactivity: Human

Specificity: Recognizes human TRB-3. Detects a band of ~28kDa by Western blot (predicted 39kDa).

Concentration: 1mg/ml

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.

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