anti-VEGF-A (human), mAb (3(6D3))

Product description: Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF-A is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.

Alternate Names/Synonyms: Vascular Endothelial Growth Factor-A; VPF

Product Type: Monoclonal Antibody

Clone: 3(6D3)

Isotype: Mouse IgG1

Immunogen: Recombinant human VEGF 165.

Applications: ELISA, FUNC, WB

Species Crossreactivity: Human

Endotoxin: <0.1EU/µg purified protein (LAL test; Lonza).

Short Term Storage: +4°C

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.

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